Transplant Infections 3rd Edition PDF

Transplant Infections 3rd Edition PDF



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Preface

The success of both the first edition of Transplant Infections, published in 1998, and the second edition, published in 2003, as a reference work to bring together information directed at the management of the infectious complications occurring specifically in immunocompromised individuals undergoing transplantation has led to the creation of this third edition. No other text focuses solely on exogenously immunosuppressed transplant patients, and no text combines solid organ and hematopoietic stem cell transplantation (historically referred to as bone marrow transplantation). Many texts focus on immunocompromised patients, but the field of transplant infectious diseases has evolved over the past 20 years as a field unto itself, with conferences devoted solely to this specialty, and guidelines, both national and international, being developed for the management of such patients. In addition, peer reviewed journals now exist which publish information on this specialized area, and training programs devoted to the subspecialty of transplant infectious diseases within the field of infectious disease are being developed.
The field of transplant infectious diseases has continued to grow and expand since the second edition was published in 2003. We have expanded the third edition to include a greater emphasis on surgical complications for each type of organ transplanted. In addition, there are new chapters on organ donor screening, drug interactions after transplantation, and new immunosuppressive agents. Chapters differentiating differences between solid organ and hematopoietic stem cell transplantation have been expanded, as have chapters discussing fungal infections, as more data accumulate for improved diagnosis and treatment and many new antifungal agents are developed. There is a new section in the cardiac transplant chapter on ventricular assist device infections, a problem the transplant infectious disease specialist must wrestle with often in patients awaiting cardiac transplantation. We have also expanded some chapters on viral infections, such as the polyomaviruses and adenovirus since recognition of the importance of these pathogens has grown. A chapter on rare viral infections has been updated as well. Transplant tourism as a topic has also been added to a section on transplant travel medicine and vaccines. A number of new authors have been added and chapters have been substantially revised or completely rewritten.
This edition remains a globally inclusive product of leading authors and investigators from around the world. Perspectives from Argentina, Brazil, Chile, New Zealand, Western Europe (Italy, Spain, Sweden, Germany, France, and Switzerland), Austria, the United States, Canada, and Israel have been synthesized in this edition.
We continue to believe that much can be learned regarding an appreciation of both the similarities and the differences in the pattern of infections and the resulting morbidity and mortality in various transplant settings. Our goal with this textbook is to provide background and knowledge for all practitioners who work with transplant patients, in order to improve both the care and outcomes of transplant recipients and to provide a framework for education of physicians, and transplant coordinators, and trainees in the field. As success in the field continues to grow we hope that this text would provide some small incremental knowledge base that would advance the field and make transplantation safer for all who need this lifesaving intervention. We thank all the contributors for their effort, and trust the reader will find this a valuable reference text as they care for transplant recipients.


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