The ABC of CBC Interpretation of Complete Blood Count & Histograms 1st Edition PDF

The ABC of CBC Interpretation of Complete Blood Count & Histograms 1st Edition PDF



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Preface

The complete blood count (CBC) is one of the most frequently ordered and routinely done investigations in the hematology laboratory. It is a Pandora’s box of information, which aids in the diagnosis of a multitude of diseases and disorders in the human body. This simple investigation, aptly labeled as the “meat and potatoes of hematology”, is economical, time-honoring, minimally invasive and exorbitantly informative.
This book is a navigation guide for students and practitioners alike related to pathology and the clinical subjects, as nearly all body ailments have direct or indirect influence on the blood picture. Hematology is all about relationships, like the relationships of the bone marrow to the systemic circulation, the plasma environment to the red cell lifespan, and hemoglobin to the red cell, so the book and you, the students and practitioners, are a vital part of this relationship.
With the changing dynamics of technology, the last decade has brought forth a radical change in hematology. The wheels of hematology have moved from predominantly manual practice to highly advanced automation. The Coulter principle and Coulter counter was landmark in the field of hematology, and the prolific Coulter’s revolutionized laboratory procedures changed the face of medicine by turning hematology guess work into accuracy. What is needed for the novice practitioner is a way to approach interpreting the visual automated data. This skill is neither necessarily practiced at university programs, nor much of the literature is available in the racks of medical libraries dedicated to the subject of CBC in this era of automation.
The book aims to help the student bridge the gap between the classroom and clinical practice; introducing the automation principles in hematology along with interpretation and deciphering of various parameters like red cell distribution width (RDW) and histograms which carry a lot of encrypted diagnostic information, because eyes can see only those things which brain knows. Although the data of the automated blood count alone will not guarantee a specific diagnosis in every case, yet does every disease have a single pattern of abnormality. Rather these values should be used to narrow the differential diagnosis as much as possible, so that more expensive and time requiring, confirmatory battery of expensive investigations like vitamin B12, folic acid, serum iron, total iron binding capacity (TIBC) estimations or Hb electrophoresis, etc. is done only selectively and invasive procedures like bone marrow aspiration and biopsy can be avoided, by proper evaluation of CBC.
The approach of the book is as simple, straightforward, and user-friendly as possible. I hope that clinical residents and consultants will find the book useful and also the text will travel with you, as you continue your career in the laboratory profession and the information will motivate you arousing your intellectual curiosity.


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