Sleisenger and Fordtran’s Gastrointestinal and Liver Disease 10th Edition PDF – 2 Volume Set

Sleisenger and Fordtran’s Gastrointestinal and Liver Disease 10th Edition PDF

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The tenth edition of Sleisenger and Fordtran’s Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management is among a select group of textbooks that have been valuable to readers over a long time span. Work by its founding editors, Marvin Sleisenger and John S. Fordtran, began more than four decades ago and culminated in the publication of the first edition, Gastrointestinal Disease, in 1973. Much has happened in the field of gastroenterology since then, and each edition of the text has methodically incorporated these exciting advances into its pages. Advances have included clearer understanding of the basic mechanisms of health and disease at a cellular, subcellular, genetic, and molecular level; a much clearer comprehension of the pathophysiology of GI and liver diseases; the introduction of numerous diagnostic tests and procedures (many of which displaced now outmoded tests and procedures); combining diagnostic with therapeutic endoscopy; developing many novel pharmaceutical agents and drug classes for conditions that previously had no such treatments; applying laparoscopic surgery in many common GI disorders; and so much more.
Over its 42-year lifespan, the textbook has had six editors: Marvin H. Sleisenger and John S. Fordtran (founding editors), as well as Mark Feldman, Bruce F. Scharschmidt, Lawrence S. Friedman, and Lawrence J. Brandt. These editors have had the good fortune to engage hundreds of superb author-contributors from around the globe who generously shared their knowledge and expertise with readers of the book. The editors also have had the luxury of stalwart support from a highly competent and professional publishing company, Elsevier, throughout the life of the book.
When the first edition of Gastrointestinal Disease was published in 1973, it was quite different from this, the tenth edition. The first edition was printed in a single volume of less than 1600 pages, with well over 200 of these pages devoted to a single entity—peptic ulcer disease. There were 115 chapters in the first edition, compared with 132 chapters in the tenth edition. Besides its two founding editors, the first edition had 55 contributors, compared with 217 contributors in the tenth edition. The first edition was written almost entirely by authors based in the United States, whereas authors from 15 countries have contributed to the pages of the tenth edition. The vast majority of chapters in the first edition were written by a single author, whereas most chapters now have two authors. And perhaps most important, there was no coverage of liver diseases in the first edition, or even in the four subsequent editions, until the sixth edition—renamed Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management—was published in 1998. In 2007, the British Medical Association awarded the eighth edition of the book its First Prize in the field of gastroenterology.
The first edition was available to readers in print format only, and color was used sparingly. As time went on, the book became available in CD-ROM and then online via a secure website. Enhanced use of color allowed improved depictions of endoscopic images and histopathology. Today the contents of the tenth edition are available on handheld devices such as smartphones, iPads, and Kindles. The online version of the tenth edition also incorporates dozens of video clips that illustrate diagnostic and therapeutic approaches in the field, with narrative descriptions of the procedures. The authors are greatly appreciative of Gregory G. Ginsberg, Christopher J. Gostout, Michael L. Kochman, Ian D. Norton, and the team at Elsevier for allowing our readers access to these valuable educational videos.
Fortunately, with the help of our distinguished contributors, the content of the textbook remains unparalleled. Comparing the contents of the first with the tenth editions, one can appreciate the striking advances in the field. Many conditions that now constitute the core of gastroenterology practice were not even known to exist in 1973. Furthermore, comparing the hepatology section in the sixth edition (1998) with that in the current edition is a striking tribute to the discoveries that have improved the diagnosis and therapy of liver disease, particularly with respect to the panorama of drugs to treat chronic viral hepatitis.
The tenth edition includes three notable chapters not included in earlier editions. An entire chapter, authored by Fergus Shanahan, has been devoted to Enteric Microbiota and another, authored by Christina Surawicz and Lawrence J. Brandt, to Probiotics and Fecal Microbiota Transplantations. These additions reflect our increasing knowledge about the bowel flora and our emerging understanding of the role of intestinal microbiota in the pathogenesis and treatment of a variety of GI (and other) diseases, most notably Clostridium difficile colitis. The editors are also delighted to welcome back John S. Fordtran who, along with Marc D. Feldman, has written a scholarly chapter on Factitious Gastrointestinal Disease, a group of disorders that can be most challenging for clinicians to diagnose and treat. Additional changes since the ninth edition are expansions of the chapter on Surgical Treatment of Obesity to include endoscopic treatment, and the chapter on Complications of Gastrointestinal Endoscopy to include preparation for endoscopy; combination of the chapters on Peptic Ulcer Disease and Treatment of Peptic Ulcer Disease into a single chapter; a new chapter on Overview of Cirrhosis; separation of the chapter on Hepatitis B and D into two chapters; and separation of the chapters on Digestion and Absorption of Nutrients and Vitamins into one on Digestion and Absorption of Macronutrients and one on Digestion and Absorption of Micronutrients. We are delighted to welcome many new authors, as well as returning authors, to the tenth edition.
Finally, the editors gratefully acknowledge the capable and spirited roles of Kate Dimock, Suzanne Toppy, Deidre (Dee) Simpson, and Cindy Thoms at Elsevier for facilitating the publication of the tenth edition. Without their support and vision, the editors would have fallen short of the high standards that were set by the founding editors and to which we remain committed.

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