Pathology and Genetics of Tumours of the Lung Pleura Thymus and Heart PDF

Pathology and Genetics of Tumours of the Lung Pleura Thymus and Heart PDF



31.78 MB PDF

   Free Download Here


Preface

With more than 1.1 million deaths annually worldwide, lung cancer is the most frequent and one of the most deadly cancer types. In men, 85-90% of cases can be attributed to tobacco smoking. Some Western countries in which the smoking habit took off about 100 years ago, tobacco control programmes have led to a significant decline in mortality. Unfortunately, the habit has now spread to many newly industrialized countries, particularly in Asia, and in Europe, there is a worrying trend of increasing smoking prevalence in young women. The prognosis of lung cancer is still poor, with 5-years survival rates of approximately 10% in most countries. Thus, primary prevention by not starting or by stopping smoking remains the most promising approach.
The association between smoking and lung cancer is not solely based on epidemiological studies. Lung tumours of smokers frequently contain a typical, though not specific, molecular fingerprint in the form of G:C > T:A mutations in the TP53 gene which are probably caused by benzo[a]pyrene, one of the many carcinogens in tobacco smoke.


If you found this book helpful then please like, subscribe and share.

Disclaimer
This site complies with DMCA Digital Copyright Laws. Please bear in mind that we do not own copyrights to this book / software. We’re sharing this with our audience ONLY for educational purpose and we highly encourage our visitors to purchase original licensed software / Books. If someone with copyrights wants us to remove this software / Book, please contact us immediately. You may send an email to myarslanlibrary@gmail.com for all DMCA/Removal Requests.