Multidisciplinary Management Of Gastrointestinal Cancers 1st Edition PDF
16.14 MB PDF
About a quarter of all diagnosed malignancies originate from the gastrointestinal (GI) system, which in nature demands multidisciplinary management because of the complexity of heterogeneity in etiology, great variations in molecular biology/ genetic characteristics, involvement of multiple organs and their distinctive functions, and the tremendous differences in treatment options and outcomes for each different disease.
With the expeditious advancement in molecular biology/genetic profile analyses (such as next generation DNA sequencing [NGS], circulating tumor cells [CTCs], cell-free DNA [cfDNA] from liquid biopsy samples, and TCGA programs) and technology (e.g. robotic surgery), as well as recent discoveries of new therapeutic agents (e.g. target-oriented agents, tyrosine kinase inhibitors [TKIs], and immune checkpoint inhibitors), multidisciplinary management for GI cancers is required to achieve the best outcome for both the individual cancer patient (personalized medicine/ precision medicine) and the general society (preventive medicine).
With the principles given above, this book is designed to provide up-to-date, evidence-based information and knowledge on the multidisciplinary management of the major malignancies in the GI system, including etiology analysis, genetic and hereditary evaluation, critical diagnostic procedures/processes, new surgical and technology advantages, the role of radiation therapy, and novel systemic agents’ development and application in clinical practice. The book also covers the significant issues of quality of life and supportive care of GI cancer patients. We hope this book may facilitate oncology practitioners, including those in all sub-specialty areas, to view and manage GI cancers with multidisciplinary perspective in their daily practice.
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